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Metabolic “Fingerprint” of Amodiaquine using on-line EC/MS. |
Posters presented at the 36th HPLC Conference in Budapest, Hungary
Recently, Electrochemistry (EC) is increasingly used to study redox reactions that take place in life sciences. Antec’s ROXY™ EC system allows to mimic many of these redox reactions within seconds that otherwise take place over several hours, weeks, months or even years in nature! The generated oxidation or reduction products are in well defined solutions, making cumbersome and costly isolation steps obsolete.
Typical applications of EC up-front MS are: prediction of drug/xenobiotic metabolism, synthesis of metabolites (ug quantities / minute), mimicking oxidative damage of DNA, cleavage of disulfide bonds in proteins/peptides, protein/peptide oxidation (stress), protein/peptide desalting prior to MS, etc.
In case of any questions feel free to contact us at support@myantec.com.