Electrochemistry/MS

Mimicking nature's redox reactions

 

• Fast synthesis of metabolites (µ-preparative)
• Rapid risk assessments of drug-protein binding
• Signal enhancement in MS
• Electrochemical cleavage of proteins/peptides
• Oxidative stress/damage of proteins, DNA, lipids, etc.

 

The on-line coupling of Electrochemistry (EC) with LC/MS has shown great potential for the investigation of drug metabolism. It offers fast electrochemical synthesis of drug metabolites for reliable quantification by mass spectrometry (MS) to be operated as a high throughput screening system. Read more about ROXY EC and ROXY EC/LC systems.

 

Prof. Uwe Karst at ASMS 2010

A video is available on our website from the oral presentation of Prof. Uwe Karst given at the ASMS 2010 early this year.

• Watch video on our website